交通性污染物对小鼠遗传毒性的影响

doi:10.3969/j.issn.1004-616x.2000.03.013

Carcinogenesis, Teratogenesis & Mutagenesis ›› 2000, Vol. 12 ›› Issue (3): 167-168.doi: 10.3969/j.issn.1004-616x.2000.03.013

Previous Articles Next Articles

THE GENETIC TOXICITY STUDY OF TRAFFIC POLLUTANT IN THE MICE

YI Yi - zhen , CHEN Lu , TANG Ming - de

Depertment of Envi ronmental Hygiene of Hunan Medical University , Changshai 　410078 , China

Received:1999-07-04 Revised:1999-12-04 Online:2000-07-30 Published:2000-07-30

Abstract

Abstract: Purpose and Methods :By Ames test , micronucleus test and sperm diformity test , the genetic toxicity was studied for mice exposed t raffic contaminated road in XIAN G YA , BAN ZAN , SON G GUI. Results and conclusion : The result s showed that there are direct and indirect mutagens in the lung tissue of contaminated mice , that the micronucleus rate of chest bone polychomatoerythrocyte ( PCE) and sperm deformity f requencies in contaminated groups were higher than cont rol group. The t raffic pollutant had genetic toxicity effect on the somatic cell and germ cell in the mice

Key words: traffic pollutant, genetic toxicity, micronucleus, sperm deformity

CLC Number:

X503

YI Yi - zhen , CHEN Lu , TANG Ming - de. THE GENETIC TOXICITY STUDY OF TRAFFIC POLLUTANT IN THE MICE[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2000, 12(3): 167-168.

[1]	SHI Wenjing, ZHANG Jiqianzhu, ZHU Jiangbo, ZHANG Xiaofang, WANG Ruina, DAI Xiaoyu, REN Lijun, TIAN Yijun. Evaluation of genotoxicity of diphenhydramine hydrochloride and caffeine compound [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2022, 34(2): 149-153,157.
[2]	CAI Qi, GAO Deyu, SHI Jianfeng, YU Hao, HAN Yan, YANG Liu, ZHAO Lei, WANG Zhaoxu. Potential use of tree shrew as an animal model for the micronucleus test [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2021, 33(5): 370-374,382.
[3]	LU Xue, TIAN Xuelei, ZHAO Hua, CAI Tianjing, TIAN Mei, LIU Qingjie. Use of the micronucleus assay to estimate partial radiation exposure dose in vitro [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2021, 33(3): 193-196.
[4]	ZHAO Hua, LU Xue, CAI Tianjing, TIAN Mei, LIU Qingjie. Effects of age and gender on formation of nucleoplasmic bridges in peripheral blood lymphocytes [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2021, 33(1): 48-52.
[5]	CAO Yiyi, LIU Weiying, YOU Xinyue, XI Jing, Chen Ruixue, ZHANG Xinyu, LUAN Yang. In vitro genotoxicity evaluation of BDE-3, BDE-47 and BDE-209 [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2020, 32(1): 15-20,28.
[6]	WANG Quankai, XIE Guangyun, MA Shunpeng, GUO Haoran, WUHAN Baolier, SONG Jiayang, XU Jianning. Genotoxicity evaluation of glycidyl methacrylate [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(6): 479-482.
[7]	LI Ying, CHEN Xiaming, LI Hanrong, LUO Te. Genotoxicity of three kinds of electric mosquito repellents on plant root tip cells [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(5): 401-405,411.
[8]	LI Ruowan, ZHOU Changhui, HUANG Pengcheng, CHANG Yan. Establishment of an in vitro PIG-A gene mutation assay based on TK6 cells for genotoxicity tests [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(3): 242-248.
[9]	WEN Hairuo, GUO Yajuan, HUANG Zhiying, WANG Xue, DAN Mo. Induction of cytotoxicity and DNA damage by iron oxide nanoparticles with different surface modifications in A549 cells [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2018, 30(6): 413-421.
[10]	XIA Ying, FU Shaohua, ZHANG Yinjing, WANG Wei. Genetic toxicity test of a pesticide, Paichongding [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2018, 30(2): 136-139.
[11]	CAO Yiyi, XI Jing, TANG Weifeng, YOU Xinyue, LIU Weiying, LUAN Yang. Genotoxicity evaluation of triclosan in vitro [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2018, 30(1): 71-75.
[12]	WANG Zhi, LING Xi, ZHANG Guowei, GAO Jianfang, ZOU Peng, JING Che, LIN Zhetao, LIU Jinyi, CAO Jia, AO Lin. Effect of folic acid on DNA demethylation and chromosomal damage in mice after their inhalation exposure to 1, 3-butadiene [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2017, 29(3): 189-193.
[13]	WANG Chao, RUAN Hongjie, DOU Jiexiong, DUAN Lian, ZHANG Hongwei. Use of the Vicia faba root tip micronucleus test to monitor the genotoxicity of tap water [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(6): 481-483,490.
[14]	WANG Chao, DUAN Lian, ZHANG Hongwei. Genetic toxicity of mercury,arsenic, formaldehyde and their combinations in Vicia faba root tip cells [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(5): 383-387.
[15]	CHEN Xiujuan, LIU Xiangmei, PANG Zengxiong, LIU Donghong, LIU Ying, LUO Xuelian, CHEN Hanjin, HUANG Yufeng. Acute and genetic toxicity of aqueous extract of Eriobotrya japonica leaves [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(5): 403-406.

THE GENETIC TOXICITY STUDY OF TRAFFIC POLLUTANT IN THE MICE

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments